AG

Advitos Gmbh

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Company Research Report: ADVITOS GmbH



1. Company Overview



Name and Mission


  • Company Name: ADVITOS GmbH

  • Mission: The mission of ADVITOS is to significantly enhance the survival of patients in intensive care units by providing effective multi-organ support systems. Their vision is to establish this support as a standard for millions of patients worldwide.


History and Founding


  • Founded: 2004 as Hepa Wash GmbH; renamed ADVITOS GmbH in 2019.

  • Founder: PD Dr. med. Bernhard Kreymann, a nephrologist with extensive medical experience in blood purification and dialysis for kidney diseases.


Key People


  • Key Person: Dr. Claus Jessen took over as Chief Executive Officer in 2022. Catherine Schreiber, associated for winning the EIT Women Leadership Award 2022.


Headquarters


  • Headquarters: Agnes-Pockels-Bogen 1, 80992 München, Germany.


Employees


  • Number of Employees: Over 75 employees.


Revenue


  • Revenue Information: No information is available.


Recognition


  • Known For: ADVITOS is renowned for the ADVOS therapy, a patented system for multi-organ support in intensive care units that integrates liver, kidney, lung support, and extracorporeal blood pH correction in a single device.


2. Products



ADVOS Multi System


  • Product Description: The ADVOS multi is an integrated multi-organ support device offering customizable treatments to focus on one or more detoxification organs simultaneously.


Key Features:


1. User Interface: Intuitive and easy-to-use information panel with dialyse-like menu navigation.
2. Support Features: Includes video-based guidance for easy setup and operation, reducing user interaction during treatment.
3. Blood Flow Control: Adjustable blood flow rates from 100 to 500 ml/min to optimize toxin removal.
4. Anticoagulation: Offers systemic and regional anticoagulation; changes during treatment without tubing replacement.
5. Flexible Treatment Duration: Allows intermittent or continuous treatment up to 24 hours.
6. Fluid Management System: Reduces the need for reverse osmosis installation at treatment sites, with an 85-liter container capacity reducing frequent bag changes.

ADVOS Verfahren (Procedure)


  • Procedure Description: An advanced extracorporeal blood purification technology for simultaneous support of kidneys, liver, and lungs, along with pH management.


Key Technologies:


1. Human Albumin Dialysis: Uses enriched dialysate for selective toxin removal.
2. pH Adjustment: Facilitates targeted treatment of metabolic or respiratory acidosis.
3. Continuous Detoxification: Unique recirculation of dialysate ensures continuous detoxification.

3. Recent Developments



Product Launches


  • New Product Announcement: A major product launch of the next generation of the ADVOS system is scheduled for 04 December 2024 in Hamburg.


Awards and Achievements


  • Awards: Won the prestigious Innovationspreis Bayern in 2020 and recognized as the most innovative medical technology company in Germany in 2021.


Partnerships and Collaborations


  • Expansion Efforts: Collaborating with German Accelerator Life Sciences to prepare for U.S. market entry and supported by the European Union’s Horizon 2020 Research and Innovation program.


Clinical Application and Studies


  • Clinical Trials: ADVOS therapy has been deployed in multiple hospitals across Europe with promising results, including applications in treating COVID-19 patients.

  • Workshops and Trainings: Regular workshops are organized to educate healthcare professionals on utilizing the ADVOS systems, with upcoming sessions planned from January to December 2025.


Management and Structural Changes


  • Leadership Change: Dr. Claus Jessen appointed as the new CEO of ADVITOS GmbH in 2022.


Strategy and Development


  • Regulatory Advances: Achieved quality management certification under DIN EN ISO 13485:2016 and the EU MDR as of 2024 for the ADVOS multi.


This report is structured to present a thorough understanding of ADVITOS GmbH, capturing their core business strategies, technological advancements, and their role in advancing intensive care treatment solutions globally.