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aurigene-discovery-technologies

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Company Research Report: Aurigene Oncology



1. Company Overview



Name:


Aurigene Oncology Limited

Mission:


Aurigene Oncology is committed to the discovery and development of novel and effective therapeutics for the treatment of cancer.

Founded:


2002 by No information is available.

Key People:


  • Brijesh Kumar Karnani, Chief Financial Officer

  • Sanjeev Giri, PhD, Senior Vice President and Head – Early Development

  • Subir Dubey, Vice President, Business Development

  • Veerendra Patil, Vice President and Head – Human Resources and Administration

  • Murali Ramachandra, PhD, Chief Executive Officer

  • Susanta Samajdar, PhD, Chief Scientific Officer

  • Akhil Kumar, MD, Chief Medical Officer


Headquarters:


39-40(P), KIADB Industrial Area, Phase II Electronics City Hosur Road Bangalore – 560100, Karnataka, India

Number of Employees:


425+ scientists

Revenue:


No information is available.

Known For:


Aurigene Oncology is known for its innovative therapeutics targeting various hallmarks of cancer. The company is recognized for its deep expertise in oncology-focused drug discovery and development, having discovered 21 novel chemical entities (NCEs) for clinical development and holding more than 200 NCE patents.

2. Products



Product Offerings:


Aurigene develops innovative therapeutics aimed at improving the lives of cancer patients. The company's pipeline leverages expertise in small molecule targeted protein degradation, immuno-oncology, precision oncology, and epigenetics.

Product Descriptions:


1. CA-170
  • Description: PD-L1/VISTA antagonist.

  • Key Features: Targets immune checkpoints to treat NSCLC, bladder, and kidney cancers.


2. AUR102
  • Description: CDK7 inhibitor.

  • Key Features: Targets breast and prostate cancers, and leukemia.


3. AUR103
  • Description: CD47 antagonist.

  • Key Features: Targets leukemia, lymphoma, and multiple solid tumors.


4. AUR104
  • Description: FABP5 inhibitor.

  • Key Features: Targets lymphoma and solid tumors.


5. AUR105
  • Description: PRMT5 inhibitor.

  • Key Features: Targets leukemia, lymphoma, and multiple solid tumors.


6. AUR106
  • Description: TIGIT antagonist.

  • Key Features: Multiple cancers.


7. AUR107
  • Description: CBP/p300 inhibitor.

  • Key Features: Targets NSCLC, lymphomas, leukemias, bladder cancers, and prostate cancers.


8. AUR108
  • Description: DHODH inhibitor.

  • Key Features: Targets leukemia and lymphoma.


9. AUR109
  • Description: DDR1/SIK2 inhibitor.

  • Key Features: Targets cancers of bladder, lung, breast, ovary, kidney, liver & lung fibrosis.


10. AUR101
  • Description: RORgt inverse agonist.

  • Key Features: Targets psoriasis, psoriatic arthritis, ankylosing spondylitis.


3. Recent Developments



Recent Developments:


  • July 5, 2022: Aurigene announced a drug discovery, development, and commercialization partnership with EQRx to combine Aurigene’s small molecule drug discovery platform and EQRx's business model to accelerate development.


  • June 9, 2022: Aurigene entered an exclusive collaboration and license agreement with Olema Oncology to develop novel cancer therapies.


  • December 14, 2021: Exelixis in-licensed a second anti-cancer compound from Aurigene following the FDA acceptance of the investigational new drug application for a Phase 1 clinical trial.


New Products Launched:


  • No information is available.


New Features Added to Existing Products:


  • No information is available.


New Partnerships:


  • Multi-program partnerships with EQRx, Exelixis, Olema Oncology, and Curis.


Conclusion:


Aurigene Oncology has established itself as a prominent player in the oncology-focused biotech landscape, demonstrating robust drug discovery capabilities and forming strategic partnerships aimed at accelerating the development of cancer therapeutics. With a strong emphasis on collaboration and innovation, Aurigene continues to make significant strides in the field of cancer treatment.
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