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biper-therapeutics

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BiPER Therapeutics Overview



BiPER Therapeutics, founded in 2021, is a biotechnology firm based in Strasbourg, France, specializing in innovative therapeutics for treating cancers with significant unmet medical needs. The company focuses on first-in-class therapeutics targeting stress pathways in cancer cells to combat resistance, specifically through the modulation of endoplasmic reticulum (ER) stress via GRP78/BiP inhibition.

Website: [biper-tx.com](https://biper-tx.com/)

Key Products and Pipeline



BiPER's pipeline is spearheaded by two small molecule candidates:

  • BPR001: Designed for the treatment of gastrointestinal cancers.

  • BPR002: Geared towards addressing melanoma.


These drug candidates implement stress induction pathways, aiming to eradicate cancer cells by compelling them to "burn out."

Leadership Team



The leadership at BiPER Therapeutics consists of seasoned professionals in fields key to the biotechnology industry:

  • Mehdi Chelbi: Chair and CEO, an accomplished leader within the life sciences sector.

  • Stéphane Rocchi: Co-founder and Board Member, with a strong background in oncology innovation.

  • Cyril Ronco: Co-founder and Board Member, expert in medicinal and organic chemistry.

  • Rachid Benida: Board Member noted for his contributions to bioactive molecule research.

  • Guillaume Vetter-Genoud: Board Member, who provides strategic insights into health ventures.


Funding and Strategic Partnerships



BiPER Therapeutics has shown effective fundraising capabilities, securing a total of €1.25 million in seed funding. This includes €800,000 in bridge funding aimed at advancing BPR001 towards clinical trials. Key investors involve WiSEED, Bpifrance, Region Grand Est, and SEMIA Incubateur.

The company seeks collaborations with pharmaceutical companies, biotech partners, and academic institutions to expand its therapeutic portfolio.

Recent Developments and Industry Participation



  • BiPER has taken part in major industry events, such as the JPMorgan Week, drawing attention from investors and pharmaceutical firms.

  • Achieved recognition as the vice-champion at the 7th Boston Biotechnology Summit's biotech pitch session.

  • Secured €800,000 in December 2024 to further the development of BPR001.


Competitor Profile



Competitive Landscape



In the biotechnology sector, with a focus on oncology therapeutics, BiPER competes with several notable firms:

  • Kite Pharma: Part of Gilead Sciences, known for pioneering in cell therapy in the immuno-oncology sector.

  • Exelixis: Based in Alameda, California, Exelixis specializes in small molecule therapies targeting various oncological conditions.

  • ImmunoMet Therapeutics: A Houston, Texas-based company creating novel therapies through cellular metabolism targeting.

  • Expansion Therapeutics and C4 Therapeutics: Both focusing on drug discovery for RNA-mediated disease treatment.


Competitive Differentiators



BiPER's strategy is centered around developing small molecule oral therapies, differentiating it from competitors like Kite Pharma which focus on cellular therapy. Its position in Europe also gives it a strategic advantage in navigating the EU regulatory landscape.

Industry Position



Operating in a competitive and fast-evolving sector, BiPER's commitment to developing "First In Class" small molecules offers a notable edge. Success in clinical trials and strategic partnerships may further solidify its competitive standing, offering innovative and accessible treatment solutions in oncology.




This comprehensive profile outlines BiPER Therapeutics and its strategic positioning within the competitive landscape, highlighting areas for potential growth and unique value propositions.
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