Culture Biosciences Market Research Report

Company Overview

• Name: Culture Biosciences

• Mission: To create a world where bioprocess is never the bottleneck.

• Founded by: No information is available

• Key People:

• Darcy Birse - Chief Executive Officer

• Sumeet Agrawal - VP of Strategy and Finance

• Lisa Krallis - VP Commercial

• Babu Sivaraman - VP of Product and R&D

• Lauren Kellogg - VP of Corporate Development

• Palmer Lam - VP of Operations

• Headquarters: San Francisco, California, USA

• Number of Employees: No information is available

• Revenue: No information is available

• What is the company known for: Culture Biosciences is known for its cloud-connected bioreactors that enable cell culture experiments with more flexibility, providing fast and accurate answers to critical bioprocess questions.

Products

Cloud-Connected Bioreactors

• Overview:

• 250mL bench-scale single-use bioreactor

• 5L single-use bioreactor

• Key Features:

• Real-time process data monitoring

• Flexible, modular design for scaling

• Designed for multiple applications: mammalian, microbial, viral vector, and media development

Software: ConsoleTM

• Overview: A secure web application for real-time experiment design, monitoring, and data analysis.

• Key Features:

• One interface for all experiments

• Remote access and collaboration capabilities

• Analytics tools and real-time monitoring

• Data science support for design of experiments (DOE)

Solutions

Culture as a Service

• Description: Bioprocess development executed in Culture’s cloud-connected labs.

• Benefits:

• Access hundreds of bioreactors without capital expenditure

• Real-time monitoring and data analytics

• Flexible capacity to meet experimental demands

Applications

• Protein Therapeutics:

• Accelerates process development, characterization, and material generation.

• Supports cell lines like CHO and HEK for protein production.

• Viral Vectors:

• Optimizes upstream process development and minimizes bottlenecks.

• Effective for various viral genome titer, capsid titer analyses, etc.

• Synthetic Biology:

• Facilitates strain screening and fermentation process optimization.

• Experienced in over 2,000 microbial strains and conducted over 20,000 successful runs.

Recent Developments

New Products/Features

• 5L Single-Use Bioreactor: Launched to address customer needs for larger process development and material generation.

• Cloud-Connected Platform: Continuous updates to software for refined user experience in design, monitoring and analysis of experiments.

Partnerships

• Collaboration with Cytiva: Partnership to ensure predictable performance from Culture’s ecosystem to higher scales of clinical or commercial production.

Research and Publications

• White papers and Case Studies:

• "Scaling up HEK cell culture process from 250mL to 5L bioreactor"

• "High-throughput Screening of Next-Gen Small Molecule Enhancers"

• "AAV Process Development in Culture Biosciences’ 250mL Bioreactors"

Industry Recognition

• Customer Testimonials:

• Positive feedback from industry leaders like Modern Meadow, Kalion, Zymergen, and Every.

• "Culture feels like an extension of our own fermentation lab, not like a CRO." - Shashway Vajpeyi, Modern Meadow

• "Culture really excels at their data platform. I haven't seen anything like it before." - Charles Tindell, Every

Service Packages

• Clone, Strain & Construct Screening

• Evaluate clones, strains, and viral constructs with seamless scale-out.

• Process Development

• Media screening and optimization experiments for process improvement.

• Process Characterization

• Characterize processes in scale-down bioreactors to fine-tune parameters.

• Process Model Development

• Develop in-silico models (Digital Twins) for process predictability.

• Scale-Out Capacity

• Utilize bioreactor capacity to meet rapid, overflow experimental needs.

Facility and Capabilities

• Laboratories: Located in San Francisco, featuring state-of-the-art bioreactors and analytical instrumentation.

• Bioreactors:

• >300 bioreactors available for various scales and process requirements.

• Compliance with stringent quality and safety standards (BSL-2, SOC2).

Analytics Capabilities

• Microbial Bioprocess: Biomass quantification, Metabolite analysis

• Mammalian Bioprocess: Viability and cell counts, Metabolite analysis, Host cell protein

• Viral Vector Analysis: Capsid titer, Viral genome titer, Empty/full ratio

No additional commentary is necessary. The data included is from the information provided.