FoundersX Ventures: Comprehensive Company Profile

Background

Overview

FoundersX Ventures is an AI-first venture capital firm established in 2016, headquartered in Menlo Park, California, with additional offices in Cambridge, Massachusetts, and New York City. The firm specializes in early-stage investments, focusing on sectors such as enterprise AI, fintech, digital health, and life sciences. Leveraging extensive research capabilities in AI infrastructure and innovative applications, FoundersX Ventures maintains a strong network of global founders and top-tier co-investors in Silicon Valley, positioning itself as a significant player in the venture capital landscape.

Mission and Vision

The firm's mission is to empower visionary founders who are defining the future through AI and deep technology innovations. By providing strategic support and capital, FoundersX Ventures aims to accelerate the growth of transformative companies that are poised to lead in their respective industries.

Industry Significance

Since its inception, FoundersX Ventures has made over 100 early-stage investments, including eight unicorns and more than 30 companies valued at over $100 million. This track record underscores the firm's significant impact on the venture capital industry, particularly in the realms of AI and digital infrastructure.

Key Strategic Focus

Core Objectives

FoundersX Ventures is committed to identifying and nurturing high-potential startups that are leveraging AI to drive innovation across various sectors. The firm's strategic focus includes:

• Deep-Dive Research: Conducting thorough market and technological analyses to identify emerging trends and opportunities.

• Contrarian Investment Approach: Embracing unconventional ideas and technologies that have the potential to disrupt existing markets.

• High Value-Add Support: Providing portfolio companies with access to top talent, long-term capital, and strategic enterprise partnerships.

Areas of Specialization

The firm's investment focus spans several key areas:

• GenAI Infrastructure: Investing in foundational compute infrastructure, including AI chips, quantum computing, and autonomous robotics, to enhance AI scalability and efficiency.

• Deep Domains: Supporting AI-driven transformations in industries such as fintech, healthcare, and enterprise solutions, utilizing cross-modality data to unlock new value.

• GenAI Agents: Backing AI applications that integrate into everyday life, improving experiences in sectors like healthcare, finance, entertainment, and commerce.

Key Technologies Utilized

FoundersX Ventures emphasizes investments in technologies that:

• Lower the cost of AI compute.

• Enhance efficiency.

• Overcome scalability bottlenecks in AI applications.

Primary Markets Targeted

The firm primarily targets markets in:

• Enterprise software as a service (SaaS).

• Financial technology (fintech).

• Digital health.

• Life sciences.

Financials and Funding

Funding History

FoundersX Ventures has successfully raised multiple funding rounds to support its investment activities. Notably, in October 2025, eight of its seed-stage portfolio companies collectively raised over $120 million in Series A funding. This achievement highlights the firm's ability to identify and support high-growth startups in the AI sector.

Notable Investors

While specific details about individual investors are not publicly disclosed, FoundersX Ventures is backed by institutional investors and has been featured in prominent publications such as The Wall Street Journal and Business Insider, reflecting its strong reputation in the venture capital community.

Utilization of Capital

The capital raised is strategically allocated to:

• Early-Stage Investments: Providing seed and Series A funding to promising startups.

• Operational Expansion: Enhancing research capabilities and expanding the firm's global presence.

• Portfolio Support: Offering strategic guidance, talent acquisition, and facilitating enterprise partnerships for portfolio companies.

Pipeline Development

Key Pipeline Candidates

FoundersX Ventures has a diverse portfolio with several notable companies:

• Jericho Security: A cybersecurity firm specializing in AI-driven solutions to combat AI-powered phishing attacks. Jericho raised $15 million in Series A funding in October 2025.

• Alinea Invest: An AI-driven wealth management platform serving over 1 million Gen Z users. Alinea secured $10 million in Series A funding in October 2025.

• Arintra: Utilizing GenAI to automate medical billing, Arintra processed over $1 billion in healthcare charges, helping customers recover millions in revenue. The company raised $21 million in Series A funding in October 2025.

• Glyphic Bio: Developing a next-generation single-molecule protein sequencing platform powered by AI, Glyphic Bio raised $38 million in Series A funding in October 2025.

Stages of Development

These companies are at various stages of development, from early-stage startups to rapidly growing enterprises, demonstrating the firm's ability to identify and nurture high-potential ventures.

Target Conditions and Timelines

The portfolio companies address a range of conditions and industries, including:

• Cybersecurity: Protecting enterprises from AI-driven threats.

• Financial Services: Enhancing wealth management for younger demographics.

• Healthcare: Improving operational efficiency through AI-driven solutions.

• Biotechnology: Advancing drug discovery and precision medicine.

Specific timelines for anticipated milestones vary by company and are aligned with their individual growth trajectories.

Technological Platform and Innovation

Proprietary Technologies

FoundersX Ventures invests in companies developing proprietary technologies that:

• Enhance AI scalability and efficiency.

• Address complex industry-specific challenges.

• Drive innovation in traditional sectors through AI integration.

Significant Scientific Methods

The firm supports the application of advanced scientific methodologies, including:

• Machine Learning Algorithms: For predictive analytics and decision-making processes.

• Data Science Techniques: To extract actionable insights from complex datasets.

• Neuroscience Applications: Particularly in digital health solutions.

AI-Driven Capabilities

FoundersX Ventures emphasizes investments in AI-driven capabilities that:

• Automate complex processes.

• Enhance personalization and user experience.

• Enable real-time data processing and decision-making.

Leadership Team

Executive Profiles

• Helen H. Liang, PhD: Founder and Managing Partner. With over 10 years of experience in the high-tech industry, Helen leads the firm in investing in entrepreneurs defining the future through enterprise AI, fintech, digital health, and biotech. She holds a PhD from the University of Wisconsin-Madison and is a member of Harvard HBS PE/VC Class 2022.

• Tom Kosnik, PhD: Partner. Tom brings extensive experience in technology commercialization and entrepreneurship, contributing to the firm's strategic direction and investment decisions.

• Sizi Chen: Product Partner. Sizi excels in the interdisciplinary research areas of neural science, machine learning, and data science, with a passion for digital health solutions that transform the healthcare industry via digital therapeutics and digital delivery of care.

Key Contributions

The leadership team has been instrumental in:

• Establishing a strong portfolio of high-growth companies.

• Expanding the firm's presence in key innovation hubs.

• Fostering strategic partnerships with leading research institutions.

Competitor Profile

Market Insights and Dynamics

The venture capital market, particularly in AI and deep technology sectors, is characterized by rapid innovation and significant competition. Investors are increasingly focusing on startups that can leverage AI to disrupt traditional industries and create new market opportunities.