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halda-therapeutics

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Halda Therapeutics Market Research Report



Company Overview



  • Name: Halda Therapeutics

  • Mission: To develop RIPTAC™ therapeutics, a new class of precision medicines to defeat cancer using a novel "hold and kill" mechanism.

  • Founded: Halda was founded by Professor Craig Crews from Yale University.

  • Key People:

  • Christian Schade: President and Chief Executive Officer, Director

  • Kat Kayser-Bricker, Ph.D.: Chief Scientific Officer

  • Scott Phillips: Chief Financial Officer

  • Scientific Founder: Craig Crews, Ph.D.

  • Headquarters: 115 Munson Street, Suite 101, New Haven, CT 06511

  • Number of Employees: No information is available.

  • Revenue: No information is available.

  • Company Known For: Developing RIPTAC™ therapeutics, a novel drug modality targeting cancer through a precision approach.


Products



RIPTAC™ Therapeutics


  • Description: Innovative heterobifunctional small molecules employing a "hold and kill" mechanism for precision cancer treatment.

  • Key Features:

  • Selectively targets tumors by holding a cancer-specific protein and a protein with essential function together.

  • Induces selective cancer cell death by abrogating essential cell functions.

  • Overcomes resistance mechanisms typical of precision oncology medications.


Recent Developments



Publications, Awards, and Appointments


  • August 7, 2024: Publication in Cell Chemical Biology showcasing proof-of-mechanism and pharmacology of RIPTAC™ therapeutics.

  • January 7, 2025: Halda Therapeutics to present at the 43rd Annual J.P. Morgan Healthcare Conference.

  • December 6, 2024: Kat Kayser-Bricker, Ph.D., receives Entrepreneur of the Year Award.

  • October 1, 2024: Christian Schade appointed as President and CEO.

  • August 12, 2024: Secured $126 million financing to advance RIPTAC™ cancer therapies into clinical trials for major solid tumors.


Recent Products and Pipeline


  • HLD-0915 for Prostate Cancer:

  • Designed to target metastatic castration-resistant prostate cancer (mCRPC) by leveraging Androgen Receptor expression.

  • Demonstrated preclinical efficacy and is expected to enter Phase 1 clinical trials in 2025.

  • Breast Cancer RIPTAC:

  • Targeting hormone receptor positive (HR+) metastatic breast cancer.

  • Currently in preclinical optimization phases.

  • Additional RIPTACs: Various programs under development to address unmet medical needs in oncology.


Partnerships and Financing


  • Raised $126 million in Series B extension financing, with support from investors such as Deep Track Capital, Frazier Life Sciences, and RA Capital Management.

  • Funding aimed at advancing RIPTAC candidates into clinical trials for prostate and breast cancer, and to develop additional products using the RIPTAC platform.


Note


  • Employee and Revenue Information: No specific data is available in the provided information.
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