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Company Research Report: Novartis AG



Company Overview


Name: Novartis AG
Mission: Reimagine medicine to improve and extend people's lives.
Vision: Become the most valued and trusted medicines company in the world.
Strategy: Deliver high-value medicines that alleviate society’s greatest disease burdens through technology leadership in R&D and novel access approaches.

Founded: No information is available
Founder(s): No information is available

Key People:
  • Fiona H. Marshall, President, Biomedical Research

  • Shreeram Aradhye, President, Development and Chief Medical Officer


Headquarters: No information is available
Number of Employees: 78,000
Revenue: No information is available
Known For: Innovative medicines reaching more than 250 million people worldwide.

Products


Product List:


1. Adakveo® (crizanlizumab)
  • Therapeutic Area: Oncology

  • Availability: USA


2. Afinitor Disperz®/Votubia® (everolimus)
  • Therapeutic Area: Oncology

  • Availability: Multiple countries including USA, Germany, Australia


3. Afinitor®/Votubia® (everolimus)
  • Therapeutic Area: Oncology

  • Availability: Multiple countries including USA, Germany, Australia


4. Aimovig® (erenumab)
  • Therapeutic Area: Neuroscience

  • Availability: USA, Russia


5. Arzerra® (ofatumumab)
  • Therapeutic Area: Oncology

  • Availability: Multiple countries including USA, Germany, Australia


6. Azarga®/Azorga® (brinzolamide, timolol)
  • Therapeutic Area: Ophthalmology

  • Availability: Germany, Australia


7. Beovu® (brolucizumab)
  • Therapeutic Area: Ophthalmology

  • Availability: USA, Russia


Description & Key Features:


No high-level descriptions or key features for the individual products are available.

Recent Developments


Latest News and Milestones:


1. Leqvio®
  • Date: August 28, 2024

  • Development: Demonstrated clinically meaningful LDL-C lowering as a monotherapy in patients at low or moderate ASCVD risk.


2. Fabhalta® (iptacopan)
  • Date: August 8, 2024

  • Development: Received FDA accelerated approval for the reduction of proteinuria in primary IgA nephropathy (IgAN).


3. Novartis Financial Results – Q2 2024
  • Date: July 18, 2024

  • Update: Continued strong sales growth and core margin expansion; raised FY 2024 bottom-line guidance.


4. Scemblix®
  • Date: July 29, 2024

  • Development: Granted FDA Priority Review for the treatment of adults with newly diagnosed CML.


New Partnerships:


1. Borealis Biosciences
  • Date: August 22, 2024

  • Development: Established through a creative deal structure involving the divestment of the legacy Chinook site.


New Features Added to Existing Products:


No information is available.

Therapeutic Areas


  • Cardiovascular, Renal and Metabolic: Focus on innovative treatments and early interventions to manage cardiovascular diseases and chronic kidney diseases.


  • Immunology: Aim to enable people with immunological conditions to live without compromise.


  • Neuroscience: Committed to changing the course of disease progression in neurological conditions.


  • Oncology: Focus on developing therapies that restore hope to those battling cancer.


Technology Platforms


1. Chemistry: Discovery of low molecular weight synthetic molecules optimized as medicines.
2. Biotherapeutics: Medicines derived from the molecules of life for specific diseases.
3. xRNA: Utilizes forms of ribonucleic acids to treat illnesses.
4. Radioligand Therapy: Delivers precision-targeted radiation to cancer cells.
5. Gene and Cell Therapy: Modifies genetic makeup for genetic or inherited diseases and uses cells for therapy delivery.

Pipeline


Selected Projects in Development:


1. AAA601 (Lutathera®)
  • Indications: GEPNET, pediatrics; Glioblastoma; 1L ES-SCLC; Gastroenteropancreatic neuroendocrine tumors

  • Development Phase: Phase 2 to Registration

2. AAA603 (177Lu-NeoB)
  • Indications: Breast cancer; Glioblastoma multiforme; Multiple solid tumors

  • Development Phase: Phase 1


3. AAA617 (Pluvicto®)
  • Indications: Metastatic hormone sensitive prostate cancer; Oligometastatic prostate cancer; Metastatic castration-resistant prostate cancer

  • Development Phase: Phase 1 to Phase 3


This report captures the most recent and relevant information about Novartis AG available as of the latest update in 2024.
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