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ranomics

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Company Research Report: Ranomics Incorporated



1. Company Overview



Name: Ranomics Incorporated

Mission: Ranomics aims to power the frontier of biological discoveries by providing ultra high-throughput screening services and tools to enable transformative discoveries using genomics.

Founded: 2015, by Leo Wan and Cathy Tie.

Key People: Leo Wan (CEO); Cathy Tie (Co-founder).

Headquarters: Toronto, Canada.

Number of Employees: No information is available.

Revenue: No information is available.

Company Specialization: Ranomics is known for its expertise in DNA synthesis, variant libraries, protein engineering, cell engineering, and genome engineering. The company is a trusted partner in custom DNA variant library synthesis and high-throughput screening services.

2. Products and Services



- DNA Variant Libraries


  • Combinatorial Libraries: Includes low diversity and combinatorial pairwise libraries.

  • Site-Saturation Libraries: Features scanning site-saturation methodologies.

  • Custom Libraries: Offers custom distribution, gene shuffle, and promoter sequence libraries.


- Protein Engineering


  • Key Features: Directed evolution, deep mutational scanning, high-throughput protein expression, yeast and mammalian cell display, analysis of protein-protein interactions, folding and stability, activity and substrate specificity, and degradation.


- Antibody Engineering


  • Key Features: Focuses on immunotherapy, biosensors, antigen epitope mapping, affinity maturation, stability, and cell-based antibody binding assays.


- Gene & Cell Therapy


  • Key Features: Specializes in AAV vector optimization, promoter optimization, CRISPR-Cas proteins engineering, RNA therapeutics, and transcriptional regulators' optimization.


- Industrial Synthetic Biology


  • Key Features: Enhances enzyme traits, metabolic engineering, strain development, and deploys proprietary bacterial spore display technology and biosensors.


- Custom Cell-Based Assays


  • Key Features: One-pot methodologies, droplet-based NGS screening, mRNA expression studies, activity optimization, and functional data generation with AI-targeting.


3. Recent Developments



  • 2019: Featured as one of the "Most Promising BioTech Solution Providers" by CIOReview.


  • 2018: Distribution agreement with Axil Scientific to provide DNA tools in Singapore. Collaboration with Science Exchange for global access to the VariantFind Mutagenesis Platform.


  • 2016-2017: Multiple strategic partnerships with Castle Medical, Beijing Genomics Institute (BGI), Veritas Genetics, and Interactive Biosoftware to classify genetic variants and utilize Ranomics' functional data.


  • 2016: Became a member of Johnson & Johnson Innovation, JLabs in Toronto.


New Products Launched: No specific new products are mentioned.

New Features Added: No specific new features introduced were documented.

New Partnerships: Partnerships with Axil Scientific, Science Exchange, Castle Medical, BGI, Veritas Genetics, and Interactive Biosoftware.

4. Conclusion



Ranomics Incorporated stands out in the biotechnology sector with its advanced, high-throughput cell and protein characterization and engineering capabilities. The company's strategic collaborations and strong foundation in scientific innovation have positioned it as a vital service provider to leading global biotechnology companies and institutions. Although specific financial data and employee numbers are unavailable, the company's influence and impact in the field are underscored by ongoing partnerships and various prestigious recognitions.
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