TB

Twist Bioscience

www.twistbioscience.com link_icon

Company Research Report: Twist Bioscience



Company Overview



  • Name: Twist Bioscience

  • Mission: Enable researchers across scientific disciplines to achieve groundbreaking discoveries, making the world safer, healthier, and more sustainable through synthetic DNA tools.

  • Founded By: Emily Leproust, CEO and Co-Founder

  • Key People:

  • Emily Leproust, PhD - CEO and Co-Founder

  • Patrick Finn - President and Chief Operating Officer

  • Adam Laponis - Chief Financial Officer

  • Nicole Moreno - Senior Vice President of Sales and Support

  • Siyuan Chen - Chief Technology Officer

  • Paula Green - Senior Vice President of Human Resources

  • Mike Fero - Chief Information Officer

  • Mark Buck - Senior Vice President of Operations

  • Bill Banyai, PhD - Senior Vice President of Advanced Development and General Manager, Data Storage

  • Angela Bitting - Chief ESG Officer, Senior Vice President of Corporate Affairs

  • Dennis Cho - Chief Legal Officer and Corporate Secretary

  • Headquarters: 681 Gateway Blvd, South San Francisco, CA 94080

  • Number of Employees: No information is available

  • Revenue: No information is available

  • Known For: Developing a proprietary semiconductor-based synthetic DNA manufacturing process that enables high-throughput synthesis, synthetic DNA tools, and biological innovations.


Products



  • Genes: Customizable Gene Synthesis solutions, offering precision and scalability for various research needs.

  • Libraries: High-diversity variant libraries for more effective genomic and antibody screens.

  • Next-Generation Sequencing (NGS): Superior target enrichment solutions, providing high-confidence variant detection and exceptional coverage.

  • Oligo Pools: High-uniformity and low-error rate oligos for a range of applications.

  • Synthetic Controls: Standards for assay development including synthetic RNA and DNA controls.

  • Antibody Services: Full suite of services for discovery and development of antibodies.


Key Features of Products



  • Gene Synthesis:

  • Gene Fragments: Delivered as linear fragments ranging from 0.3 kb to 5.0 kb.

  • Clonal Genes: Provided in the vector of choice, with customization options for length and yield.

  • High-Quality: High-throughput, scalable, and affordable gene manufacturing with low error rates.

  • Variant Libraries:

  • Combinatorial and Site Saturation Variants: For comprehensive screening and protein engineering.

  • High Diversity: Up to 10^10 unique variants assured precision in experimental research.

  • NGS Target Enrichment Panels:

  • Customizable with high fidelity probes and scalable panel sizes.

  • Rapid turnaround times and precision in variant detection.

  • Oligo Pools:

  • Ability to synthesize pools containing thousands of custom sequences.

  • Precision synthesis up to 300nt, high uniformity and data confidence.


Recent Developments



  • Partnership with MedGenome: Established HOPE for Rare Diseases Program in India to provide discounted whole exome sequencing for economically disadvantaged families.

  • Advancements in Multiplexed Gene Fragments: Expanded offering to provide pooled dsDNA synthesis up to 500bp, facilitating more efficient high-throughput screening processes.

  • Expansion in Synthetic Viral Controls: Enhanced portfolio to cover a range of pathogens, with flexible and safe assay-ready control configurations.


New Products and Features



  • MRD Rapid 500 Panel: Launched to monitor minimal residual disease in a scalable manner with rapid turnaround of custom design panels.

  • Advanced NGS and Synthetic Biology Tools: Developed applications for cancer research and clinical oncology. These tools support target identification, therapeutic development, and diagnostic monitoring.


Partnerships



  • Biopharma Collaborations: Collaborating with industry players for advanced therapeutic discovery and development through antibody libraries and discovery services.

  • NGS ProLab and Channel Partners: Expanding reach through strategic alliances and distribution channels.


Conclusion



Twist Bioscience stands out as a leader in synthetic DNA manufacturing, providing cutting-edge products and solutions to enable a wide array of scientific research and discovery. Their focus on partnerships and technological advancements ensures they remain at the forefront of the bioscience sector.