LinkedIn: [Ann Tilley, MD](http://www.linkedin.com/in/ann-tilley-md-39b48867)
Location: New York City Metropolitan Area
Professional Overview
Dr. Ann Tilley is a medical doctor affiliated with Lenox Hill Hospital and is noted for her expertise in pulmonary medicine and genetic medicine, particularly relating to respiratory disease. Although her primary institutional affiliation is Lenox Hill Hospital, she is connected and recognized professionally within Advanced Imaging and Radiology contexts, likely indicating collaboration or influence in radiologic and imaging aspects of pulmonary diagnostics.
Education and Credentials
- Washington University in St. Louis (1997–2001)
- Undergraduate institution (1993–1997) — details obscured in source
- Board Certifications from the American Board of Internal Medicine in:
- Critical Care Medicine
- Internal Medicine
- Pulmonary Disease
Current Professional Roles and Affiliations
- Medical professional at Lenox Hill Hospital
- Member and Fellow of:
- American College of Chest Physicians
- American Thoracic Society
Dr. Tilley holds positions that reflect advanced clinical practice and medical research involvement, especially with focus on pulmonary diseases and critical care.
Research and Publication Highlights
Dr. Tilley has a substantial record of peer-reviewed publications focusing on the impact of smoking on lung structure and function, particularly at the molecular and cellular level. Her research contributes to the understanding of pulmonary pathology, notably:
- Smoking-Induced Lung Aging: Demonstrated significant dysregulation of 18 aging-related genes in the small airway epithelium of smokers, along with a 14% reduction in telomere length, providing biologic evidence of accelerated lung aging due to smoking ([Respiratory Research, 2014](https://www.ncbi.nlm.nih.gov/pubmed/25248511)).
- Persistence of miRNA Dysregulation Despite Smoking Cessation: Investigated molecular changes that persist in small airway epithelium even after smoking cessation, indicating long-term molecular impacts of tobacco exposure.
- Intraflagellar Transport (IFT) and COPD: Research identified downregulation of 8 IFT-related genes in smokers correlating with shorter cilia lengths, substantiating mechanisms contributing to impaired mucociliary clearance in COPD patients ([PLOS One, 2014](https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0085453)). This work suggests potential therapeutic avenues focused on normalizing cilia length.
Her research is frequently published in high-impact journals such as PLOS One and has been cited widely, positioning her as a recognized authority in respiratory genetic medicine and pulmonary pathophysiology.
Clinical and Research Interests
- Smoking-related pulmonary pathology
- Molecular aging processes in lung tissue
- Chronic Obstructive Pulmonary Disease (COPD) mechanisms
- Genetic and molecular markers in respiratory medicine
- Advanced imaging correlation with pulmonary function and disease progression
Her insights bridge clinical pulmonary care and molecular genetics, aligning with diagnostic radiology's evolving role in detecting and evaluating lung disease through advanced imaging.
Industry and Professional Impact
Ann Tilley’s involvement with leading professional organizations and her research focus on detailed pathophysiological mechanisms relevant to COPD and smoking-related lung disease establish her as a key opinion leader at the intersection of pulmonology, radiology, and translational genetic medicine. Her work informs diagnostic strategies and underscores the importance of advanced imaging modalities in assessing lung structure and function decline.
Her affiliation with Advanced Imaging And Radiology, alongside Lenox Hill Hospital, demonstrates a clinical-scientific framework where advanced imaging and molecular diagnostics converge, offering potential collaboration or educational opportunities regarding imaging modalities that enhance understanding of pulmonary disease progression.
Additional Notes
- Dr. Tilley maintains an active professional online presence with over 500 connections and 549 followers on LinkedIn, indicating a well-established and credible profile within the medical community.
- The visibility of her research and clinical updates suggests openness to professional networking and collaboration across pulmonary medicine and imaging specialties.
The detailed research and clinical background of Dr. Ann Tilley provide actionable insights into advanced pulmonary imaging needs and underline her role in bridging clinical care with molecular research, making her a pivotal professional contact within Advanced Imaging And Radiology and affiliated respiratory care networks.
