Tyler Benedum

Chief Technical Officer

Professional Overview

Tyler Benedum is an accomplished executive with extensive expertise in pharmaceutical development and operations. As the Chief Technical Officer at Aktis Oncology and the Vice President of CMC Development at Avid Radiopharmaceuticals, he leverages his deep technical knowledge and strategic leadership to drive innovation and ensure the successful advancement of novel therapeutics.

Experience Summary

Current Roles

Chief Technical Officer, Aktis Oncology (Present)

• Responsible for overseeing all technical and operational aspects of the company's oncology pipeline, including product development, manufacturing, and quality assurance

• Leads a team of experienced scientists and engineers to optimize production processes and ensure the delivery of high-quality, clinically-effective cancer treatments

• Collaborates closely with cross-functional teams to align technical strategies with the company's overall business objectives

Vice President, CMC Development, Avid Radiopharmaceuticals (Present)

• Spearheads the chemistry, manufacturing, and controls (CMC) development for Avid's portfolio of innovative radiopharmaceuticals

• Manages a team of subject matter experts to ensure the seamless scale-up and commercialization of the company's lead drug candidates

• Provides strategic guidance to the executive leadership team on technical matters, regulatory compliance, and operational efficiency

Career Progression

Prior to his current roles, Tyler held various technical and leadership positions within the pharmaceutical industry, including:

• Director of Process Development, Merck & Co.

• Senior Scientist, Pfizer Inc.

• Research Associate, University of Pennsylvania

Throughout his career, Tyler has demonstrated a consistent track record of driving successful drug development programs and implementing robust quality management systems. His expertise in areas such as process optimization, technology transfer, and regulatory compliance has been instrumental in advancing multiple therapeutic candidates from the laboratory to the clinic.

Academic Background

Tyler holds a Ph.D. in Pharmaceutical Sciences from the University of Pennsylvania, where he specialized in drug delivery and formulation development. He also earned a Bachelor of Science degree in Chemical Engineering from the University of Delaware.

Areas of Expertise

• Pharmaceutical product development and scale-up

• Chemistry, manufacturing, and controls (CMC) strategy

• Regulatory compliance and quality assurance

• Operational excellence and process optimization

• Multidisciplinary team leadership and collaboration

Professional Impact

Under Tyler's technical leadership, Aktis Oncology has successfully navigated the critical development stages of its lead oncology candidates, advancing multiple programs into late-stage clinical trials. Additionally, his contributions to Avid Radiopharmaceuticals have been instrumental in the company's ability to rapidly progress its portfolio of novel radiopharmaceuticals, positioning it as a leader in the field of targeted cancer therapy.

Conclusion

With a proven track record of driving innovation and operational excellence in the pharmaceutical industry, Tyler Benedum is a respected technical leader poised to continue making a significant impact on the development and delivery of transformative cancer treatments.